Journal: Neurorehabilitation and neural repair
Article Title: Abnormal EEG responses to TMS during the cortical silent period are associated with hand function in chronic stroke
doi: 10.1177/1545968317712470
Figure Lengend Snippet: Evaluation of the TMS-evoked silent period. A. Colored traces represent rectified EMG data recorded from the abductor pollicis brevis muscle contralateral to TMS for a single control participant. All trials are illustrated (colored lines) and the mean value calculated across trials is represented by the bolded trace (black line). Vertical red lines indicate the onset and offset of the TMS-evoked EMG silent period. B. Waveforms represent TMS-evoked potentials (TEPs) recorded (averaged across trials) from 32 scalp EEG channels during silent period evaluation. Topographic head plots illustrate the temporal evolution of the TEPs at specific latencies of interest (P30, N45, P60, N100, P180, N280) and at a single time point (−50ms) prior to stimulation onset (0ms). Note that TEPs in each channel generally return to baseline around 400ms after TMS delivery. Red dot denotes the EEG channel of interest (Cz) for statistical analyses. C. Group-mean averaged TEPs recorded during silent period assessment. Uncorrected group mean TEPs recorded from Cz during TMS delivered over iM1 in the stroke group (n = 12, blue) compared to TMS delivered over ndM1 in the control group (n = 12, green) are shown. Standard error is represented by shaded areas. Data: −100 ms to 500 ms relative to TMS delivery (red dashed line). In these tracings, statistical outliers for amplitudes and latencies have not been removed. Inset: head plot depicting location of Cz. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
Article Snippet: Transcranial magnetic stimulation Single TMS pulses were delivered using a figure-of-eight 70mm coil (Magstim Company Ltd, Dyfed, UK) connected to a monophasic stimulator (Magstim 200 2 ).
Techniques: Control